Dr.Chitra Arasada

Dr.Veera Venkata Satyanarayana Kunche, Dr.V.V. Lakshmi Narasimha Rao, Dr.Ravinaini Kosti

Abstract

STUDY DESIGN: HOSPITAL BASED INTERVENTIONAL STUDY
PURPOSE: TO STUDY THE SHORT TERM AFFECT OF 2% PILOCARPINE ON IOP WHEN USED TO INDUCE MIOSIS BEFORE LPI.
METHODS: 30 PATIENTS (60 EYES ) WITH ANGLE CLOSURE DISEASE REQUIRING LPI WERE STUDIED.
BASELINE IOP WAS MEASURED BEFORE INSTILLING 2% PILO , THEN PILO WAS INSTILLED FOR EVERY 15 MIN FOR AN HOUR.
4 IOP RECORDINGS WERE TAKEN BEFORE LPI. PERCENTAGE OF IOP REDUCTION WAS CALCULATED
RESULTS : MEAN OF RIGHT EYES (RE )BEFORE PILO IS 17.8 , LEFT EYES (LE )IS 18.4 , COMBINED IS 18.1.
STANDARD DEVIATION (SD )RE BEFORE PILO 7.51 , LE IS 8.25 , COMBINED IS 7.82
MEAN OF RE AFTER PILO IS 14.7 , LE – 15.0 , COMBINED IS 14.8
STANDARD DEVIATION AFTER PILO RE -6.27 , LE -6.63.COMBINED -6.39
THIS GIVES TOTAL MEAN OF IOP BEFORE PILO – 18.10 , AFTER PILO -14.43, SD BEFORE PILO-7.82 , AFTER PILO -6.39
P VALUE – 0.001 ( PAIRED SAMPLE T TEST )
CONCLUSION = THE RESULTS SHOW A SIGNIFICANT DECREASE IN IOP AFTER SHORT TERM INSTILLATION OF PILOCARPINE