Dr. Ekagrata

Dr.Swasti Pandey, Dr. Deepak Mishra

Abstract

Purpose: The current study was aimed to find correlation of glycosylated hemoglobin with retinal nerve fibre layer thickness(RNFLT) and Central macular thickness(CMT) in diabetic population in North India. Methods: This was a crosssectional observational study of 300 diabetic patients divided in 150 equal groups without and with retinopathy and 150 people were included as control. Along with that blood investigations were ordered including Fasting(FBS) and post Quantitative variables were compared using One way ANOVA or Kruskal Wallis test was applied for inter-group comparison followed by a Student Newman Keuls test. Results RNFL thinning was found in all four quadrants in diabetics irrespective of the status of retinopathy (p-0value=0.000) with a significant negative correlation of glycosylated haemoglobin values with RNFLT in the inferior(r value= -0.300,p-value=0.000) and superior (r value= -0.236,p-value=0.004) quadrants of right eyes and in inferior(r value=-0.